Searchable abstracts of presentations at key conferences in endocrinology
ea0077p235 | Reproductive Endocrinology | SFEBES2021
Wilms’ Tumour-1 (WT1) regulates proliferation, apoptosis and endocrine function in a model of human granulosa cells
Background: The WilmsÂ’ Tumour-1 (WT1) transcription factor is a critical regulator of embryonic gonadogenesis, but is also expressed by granulosa cells (GCs) in preantral follicles in the ovary after birth. Evidence from animal models suggests an important role for WT1 in regulating GC steroidogenesis and apoptosis. However, the role of WT1 in human GC biology has not been extensively explored.Aim: To investigate the role of WT1 in regulating human ...
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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